Cryoprotein Produced by Clostridium botulinum Type G

Production of phenylacetic and hydroxyphenylacetic acids by clostridium botulinum type G.

Phenylacetic and hydroxyphenylacetic acids were present as major acids in spent growth medium from Clostridium botulinum type G. These aromatic acids were identified by gas-liquid chromatography and mass spectrometry.

Effect of water activity and pH on growth and toxin production by Clostridium botulinum type G.

The combined effect of water activity (aw) and pH on growth and toxin production by Clostridium botulinum type G strain 89 was investigated. The minimum aw at which growth and toxin formation occurred was 0.965, for media in which the pH was adjusted with either sodium chloride or sucrose. The minimum pH (at the optimum aw) for growth and toxin production of C. botulinum type G was found to be ...

Transdermal Delivery of Clostridium Botulinum Toxin Type a by Iontophoresis

Activation of Clostridium botulinum type E toxin by trypsin.

Since 1936, when the type E strain of Clostridium botulinum was first established as a result of the work of Gunnison et al. (1936), 17 outbreaks of Type E botulism have been reported, involving 69 persons, of whom 21 died (Dolman and Chang, 1953; Dolman et al., 1955). Although the large proportion of fatalities suggests that this organism is highly toxigenic, published reports indicate that in...

Clostridium botulinum Type D Lysogenized Organisms

We examined production of ADP-ribosyltransferase C3 in 11 strains of Clostridium botldinum type C and D and their nontoxigenic derivatives. Antisera to C3 proteins of type C organisms divided C3 proteins roughly into at least two groups, bearing no relation to their bacterial types. The C3 gene of type D strain South African was isolated from a toxigenic phage library, and the complete sequence...